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Biomolecular interactions of small-molecule inhibitors affecting the YopH protein tyrosine phosphatase
We have developed competitive and direct binding methods to examine small-molecule inhibitors of protein tyrosine phosphatase (PTPase) activity. Focusing on the Yersinia outer protein H (YopH), a potent bacterial PTPase, we describe how an understanding of the kinetic interactions involving YopH, pe...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3573263/ https://ncbi.nlm.nih.gov/pubmed/23241354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12097 |
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