FTO levels affect RNA modification and the transcriptome

A block of single-nucleotide polymorphisms within intron 1 of the FTO (fat mass and obesity associated) gene is associated with variation in body weight. Previous works suggest that increased expression of FTO, which encodes a 2-oxoglutarate-dependent nucleic acid demethylase, leads to increased bod...

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Main Authors: Berulava, Tea, Ziehe, Matthias, Klein-Hitpass, Ludger, Mladenov, Emil, Thomale, Jürgen, Rüther, Ulrich, Horsthemke, Bernhard
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573201/
https://ncbi.nlm.nih.gov/pubmed/22872099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.168
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