N6-Adenosine Methylation in MiRNAs

Methylation of N6-adenosine (m6A) has been observed in many different classes of RNA, but its prevalence in microRNAs (miRNAs) has not yet been studied. Here we show that a knockdown of the m6A demethylase FTO affects the steady-state levels of several miRNAs. Moreover, RNA immunoprecipitation with...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Berulava, Tea, Rahmann, Sven, Rademacher, Katrin, Klein-Hitpass, Ludgar, Horsthemke, Bernhard
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344304/
https://ncbi.nlm.nih.gov/pubmed/25723394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118438
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