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The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels
As shown by genome-wide association studies single-nucleotide polymorphisms (SNPs) within intron 1 of the FTO gene are associated with the body mass index and type II diabetes, although the functional significance of these SNPs has remained unclear. Using primer extension assays, we have determined...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987405/ https://ncbi.nlm.nih.gov/pubmed/20512162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.71 |
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