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The obesity-associated Fto gene is a transcriptional coactivator

The fat mass and obesity associated, FTO, gene has been shown to be associated with obesity in human in several genome-wide association scans. In vitro studies suggest that Fto may function as a single-stranded DNA demethylase. In addition, homologous recombination-targeted knockout of Fto in mice r...

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Detalhes bibliográficos
Main Authors: Wu, Qiong, Saunders, Rudel A., Szkudlarek-Mikho, Maria, de la Serna, Ivana, Chin, Khew-Voon
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963669/
https://ncbi.nlm.nih.gov/pubmed/20858458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.09.064
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