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The obesity-associated Fto gene is a transcriptional coactivator
The fat mass and obesity associated, FTO, gene has been shown to be associated with obesity in human in several genome-wide association scans. In vitro studies suggest that Fto may function as a single-stranded DNA demethylase. In addition, homologous recombination-targeted knockout of Fto in mice r...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963669/ https://ncbi.nlm.nih.gov/pubmed/20858458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.09.064 |
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