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FTO levels affect RNA modification and the transcriptome
A block of single-nucleotide polymorphisms within intron 1 of the FTO (fat mass and obesity associated) gene is associated with variation in body weight. Previous works suggest that increased expression of FTO, which encodes a 2-oxoglutarate-dependent nucleic acid demethylase, leads to increased bod...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Nature Publishing Group
2013
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3573201/ https://ncbi.nlm.nih.gov/pubmed/22872099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.168 |
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