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Self-Administration of Cocaine Induces Dopamine-Independent Self-Administration of Sigma Agonists
Sigma(1) receptors (σ(1)Rs) are intracellularly mobile chaperone proteins implicated in several disease processes, as well as psychiatric disorders and substance abuse. Here we report that although selective σ(1)R agonists (PRE-084, (+)-pentazocine) lacked reinforcing effects in drug-naive rats, ove...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572457/ https://ncbi.nlm.nih.gov/pubmed/23187725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.224 |
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