Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors

Sigma receptor (σR) antagonists attenuate many behavioral effects of cocaine but typically not its reinforcing effects in self-administration procedures. However, the σR antagonist rimcazole and its N-propylphenyl analogs, [3-(cis-3,5-dimethyl-4-[3-phenylpropyl]-1-piperazinyl)-propyl]diphenylamine h...

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Bibliographic Details
Main Authors: Hiranita, Takato, Soto, Paul L., Kohut, Stephen J., Kopajtic, Theresa, Cao, Jianjing, Newman, Amy H., Tanda, Gianluigi, Katz, Jonathan L.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2011
Subjects:
Behavioral Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199989/
https://ncbi.nlm.nih.gov/pubmed/21859929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.185025
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