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σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration

Several N-substituted benztropine (BZT) analogs are atypical dopamine transport inhibitors as they have affinity for the dopamine transporter (DAT) but have minimal cocaine-like pharmacologic effects and can block numerous effects of cocaine, including its self-administration. Among these compounds,...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Hiranita, Takato, Hong, Weimin C., Kopajtic, Theresa, Katz, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454590/
https://ncbi.nlm.nih.gov/pubmed/28442581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241109
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