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Reinforcing Effects of σ-Receptor Agonists in Rats Trained to Self-Administer Cocaine

σ-Receptor (σR) antagonists have been reported to block certain effects of psychostimulant drugs. The present study examined the effects of σR ligands in rats trained to self-administer cocaine (0.032–1.0 mg/kg/inj i.v.) under fixed-ratio 5-response schedules of reinforcement. Maximal rates of respo...

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Hlavní autoři: Hiranita, Takato, Soto, Paul L., Tanda, Gianluigi, Katz, Jonathan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812106/
https://ncbi.nlm.nih.gov/pubmed/19892920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.159236
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