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Lack of Cocaine-Like Discriminative-Stimulus Effects of σ Receptor Agonists in Rats
Previous studies demonstrated effectiveness of selective sigma-receptor (σR) agonists (DTG, PRE-084) as reinforcers in rats trained to self-administer cocaine. Like cocaine, these drugs increased nucleus accumbens shell dopamine levels, and effects of DTG, but not PRE-084, on dopamine appeared to be...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666342/ https://ncbi.nlm.nih.gov/pubmed/21808192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e328349ab22 |
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