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Lack of Cocaine-Like Discriminative-Stimulus Effects of σ Receptor Agonists in Rats

Previous studies demonstrated effectiveness of selective sigma-receptor (σR) agonists (DTG, PRE-084) as reinforcers in rats trained to self-administer cocaine. Like cocaine, these drugs increased nucleus accumbens shell dopamine levels, and effects of DTG, but not PRE-084, on dopamine appeared to be...

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書誌詳細
主要な著者: Hiranita, Takato, Soto, Paul L., Tanda, Gianluigi, Katz, Jonathan L.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666342/
https://ncbi.nlm.nih.gov/pubmed/21808192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e328349ab22
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