Modafinil potentiates cocaine self-administration by a dopamine-independent mechanism: possible involvement of gap junctions

Modafinil and methylphenidate are medications that inhibit the neuronal reuptake of dopamine, a mechanism shared with cocaine. Their use as “smart drugs” by healthy subjects poses health concerns and requires investigation. We show that methylphenidate, but not modafinil, maintained intravenous self...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Mereu, Maddalena, Hiranita, Takato, Jordan, Chloe J., Chun, Lauren E., Lopez, Jessica P., Coggiano, Mark A., Quarterman, Juliana C., Bi, Guo-Hua, Keighron, Jacqueline D., Xi, Zheng-Xiong, Newman, Amy Hauck, Katz, Jonathan L., Tanda, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360549/
https://ncbi.nlm.nih.gov/pubmed/32340023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0680-5
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