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Lack of Specific Involvement of (+)-Naloxone and (+)-Naltrexone on the Reinforcing and Neurochemical Effects of Cocaine and Opioids

Effective medications for drug abuse remain a largely unmet goal in biomedical science. Recently, the (+)-enantiomers of naloxone and naltrexone, TLR4 antagonists, have been reported to attenuate preclinical indicators of both opioid and stimulant abuse. To further examine the potential of these com...

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Bibliografski detalji
Izdano u:Neuropsychopharmacology
Glavni autori: Tanda, Gianluigi, Mereu, Maddalena, Hiranita, Takato, Quarterman, Juliana C, Coggiano, Mark, Katz, Jonathan L
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026747/
https://ncbi.nlm.nih.gov/pubmed/27296151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.91
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