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shRNA and siRNA Delivery to the Brain

The limiting factor in in vivo RNA interference (RNAi) is delivery. Drug delivery methods that are effective in cell culture may not be practical in vivo for intravenous RNAi applications. Nucleic acid drugs are highly charged and do not cross cell membranes by free diffusion. Therefore, the in vivo...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Príomhúdar: Pardridge, William M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572210/
https://ncbi.nlm.nih.gov/pubmed/17434235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2007.03.008
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