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Exploring Functional In Vivo Consequences of the Selective Genetic Ablation of mTOR Signaling in T Helper Lymphocytes

The mammalian Target of Rapamycin (mTOR) defines a crucial link between nutrient sensing and immune function. In CD4+ T cells, mTOR has been shown to play a critical role in regulating effector and regulatory T cell differentiation as well as the decision between full activation versus the induction...

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Autori principali: Delgoffe, Greg M., Powell, Jonathan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571700/
https://ncbi.nlm.nih.gov/pubmed/22125075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-430-8_20
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