Activating HER2 mutations in HER2 gene amplification negative breast cancer

Data from eight breast cancer genome sequencing projects identified 25 patients with HER2 somatic mutations in cancers lacking HER2 gene amplification. To determine the phenotype of these mutations, we functionally characterized thirteen HER2 mutations using in vitro kinase assays, protein structure...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bose, Ron, Kavuri, Shyam M., Searleman, Adam C., Shen, Wei, Shen, Dong, Koboldt, Daniel C., Monsey, John, Goel, Nicholas, Aronson, Adam B., Li, Shunqiang, Ma, Cynthia X., Ding, Li, Mardis, Elaine R., Ellis, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570596/
https://ncbi.nlm.nih.gov/pubmed/23220880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0349
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados