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The Evolutionary History of Amino Acid Variations Mediating Increased Resistance of S. aureus Identifies Reversion Mutations in Metabolic Regulators

The evolution of resistance in Staphylococcus aureus occurs rapidly, and in response to all known antimicrobial treatments. Numerous studies of model species describe compensatory roles of mutations in mediating competitive fitness, and there is growing evidence that these mutation types also drive...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Champion, Mia D., Gray, Vanessa, Eberhard, Carl, Kumar, Sudhir
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570469/
https://ncbi.nlm.nih.gov/pubmed/23424663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056466
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