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The Evolutionary History of Amino Acid Variations Mediating Increased Resistance of S. aureus Identifies Reversion Mutations in Metabolic Regulators

The evolution of resistance in Staphylococcus aureus occurs rapidly, and in response to all known antimicrobial treatments. Numerous studies of model species describe compensatory roles of mutations in mediating competitive fitness, and there is growing evidence that these mutation types also drive...

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書誌詳細
主要な著者: Champion, Mia D., Gray, Vanessa, Eberhard, Carl, Kumar, Sudhir
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570469/
https://ncbi.nlm.nih.gov/pubmed/23424663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056466
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