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Control of TMEM16A by INO-4995 and other inositolphosphates
BACKGROUND AND PURPOSE: Ca(2+)-dependent Cl(−) secretion (CaCC) in airways and other tissues is due to activation of the Cl(−) channel TMEM16A (anoctamin 1). Earlier studies suggested that Ca(2+)-activated Cl(−) channels are regulated by membrane lipid inositol phosphates, and that 1-O-octyl-2-O-but...
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Blackwell Publishing Ltd
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570019/ https://ncbi.nlm.nih.gov/pubmed/22946960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02193.x |
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