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Genome-Wide Association Analysis of Imputed Rare Variants: Application to Seven Common Complex Diseases

Genome-wide association studies have been successful in identifying loci contributing effects to a range of complex human traits. The majority of reproducible associations within these loci are with common variants, each of modest effect, which together explain only a small proportion of heritabilit...

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Main Authors: Mägi, Reedik, Asimit, Jennifer L, Day-Williams, Aaron G, Zeggini, Eleftheria, Morris, Andrew P
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569874/
https://ncbi.nlm.nih.gov/pubmed/22951892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21675
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