The effect of genome-wide association scan quality control on imputation outcome for common variants

Imputation is an extremely valuable tool in conducting and synthesising genome-wide association studies (GWASs). Directly typed SNP quality control (QC) is thought to affect imputation quality. It is, therefore, common practise to use quality-controlled (QCed) data as an input for imputing genotypes...

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Detalhes bibliográficos
Main Authors: Southam, Lorraine, Panoutsopoulou, Kalliope, Rayner, N William, Chapman, Kay, Durrant, Caroline, Ferreira, Teresa, Arden, Nigel, Carr, Andrew, Deloukas, Panos, Doherty, Michael, Loughlin, John, McCaskie, Andrew, Ollier, William E R, Ralston, Stuart, Spector, Timothy D, Valdes, Ana M, Wallis, Gillian A, Wilkinson, J Mark, Marchini, Jonathan, Zeggini, Eleftheria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083623/
https://ncbi.nlm.nih.gov/pubmed/21267008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.242
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