Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data

OBJECTIVES: Obesity as measured by body mass index (BMI) is one of the major risk factors for osteoarthritis. In addition, genetic overlap has been reported between osteoarthritis and normal adult height variation. We investigated whether this relationship is due to a shared genetic aetiology on a g...

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Hauptverfasser: Elliott, Katherine S, Chapman, Kay, Day-Williams, Aaron, Panoutsopoulou, Kalliope, Southam, Lorraine, Lindgren, Cecilia M, Arden, Nigel, Aslam, Nadim, Birrell, Fraser, Carluke, Ian, Carr, Andrew, Deloukas, Panos, Doherty, Michael, Loughlin, John, McCaskie, Andrew, Ollier, William E R, Rai, Ashok, Ralston, Stuart, Reed, Mike R, Spector, Timothy D, Valdes, Ana M, Wallis, Gillian A, Wilkinson, Mark, Zeggini, Eleftheria
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2013
Schlagworte:
Clinical and Epidemiological Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664369/
https://ncbi.nlm.nih.gov/pubmed/22956599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-202081
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