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Defining the power limits of genome-wide association scan meta-analyses

Large-scale meta-analyses of genome-wide association scans (GWAS) have been successful in discovering common risk variants with modest and small effects. The detection of lower frequency signals will undoubtedly require concerted efforts of at least similar scale. We investigate the sample size-dict...

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Detalhes bibliográficos
Main Authors: Chapman, Kay, Ferreira, Teresa, Morris, Andrew, Asimit, Jennifer, Zeggini, Eleftheria
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428938/
https://ncbi.nlm.nih.gov/pubmed/21922540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20627
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