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Synthetic associations in the context of genome-wide association scan signals

Genome-wide association studies (GWAS) have successfully identified a large number of genetic variants associated with complex traits, but these only explain a small proportion of the total heritability. It has been recently proposed that rare variants can create ‘synthetic association' signals...

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Detalhes bibliográficos
Main Authors: Orozco, Gisela, Barrett, Jeffrey C., Zeggini, Eleftheria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953742/
https://ncbi.nlm.nih.gov/pubmed/20805105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq368
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