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Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals
Synthetic associations have been posited as a possible explanation for missing heritability in complex disease. We show several lines of evidence which suggest that, while possible, these synthetic associations are not common.
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3022527/ https://ncbi.nlm.nih.gov/pubmed/21267062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000580 |
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