Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells

The nonhomologous DNA end-joining (NHEJ) pathway contains six known components, including Artemis, a nuclease mutated in a subset of human severe combined immunodeficient patients. Mice doubly deficient for the five previously analyzed NHEJ factors and p53 inevitably develop progenitor B lymphomas h...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Rooney, Sean, Sekiguchi, JoAnn, Whitlow, Scott, Eckersdorff, Mark, Manis, John P., Lee, Charles, Ferguson, David O., Alt, Frederick W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14983023/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308757101
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak