Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells
The nonhomologous DNA end-joining (NHEJ) pathway contains six known components, including Artemis, a nuclease mutated in a subset of human severe combined immunodeficient patients. Mice doubly deficient for the five previously analyzed NHEJ factors and p53 inevitably develop progenitor B lymphomas h...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356964/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14983023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308757101 |
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