Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation

The aim of this study was to design, develop, and optimize respirable tacrolimus microparticles and nanoparticles and multifunctional tacrolimus lung surfactant mimic particles for targeted dry powder inhalation delivery as a pulmonary nanomedicine. Particles were rationally designed and produced at...

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Bibliographic Details
Main Authors: Wu, Xiao, Hayes, Don, Zwischenberger, Joseph B, Kuhn, Robert J, Mansour, Heidi M
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2013
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569053/
https://ncbi.nlm.nih.gov/pubmed/23403805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S40166
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