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Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery

The aim of this study was to design and develop respirable antibiotics moxifloxacin (MOXI) hydrochloride and ofloxacin (OFLX) microparticles and nanoparticles, and multifunctional antibiotics particles with or without lung surfactant 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) for targeted dr...

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Detalhes bibliográficos
Main Authors: Duan, Jinghua, Vogt, Frederick G, Li, Xiaojian, Hayes, Don, Mansour, Heidi M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787929/
https://ncbi.nlm.nih.gov/pubmed/24092972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S48631
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