Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery

The aim of this study was to design and develop respirable antibiotics moxifloxacin (MOXI) hydrochloride and ofloxacin (OFLX) microparticles and nanoparticles, and multifunctional antibiotics particles with or without lung surfactant 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) for targeted dr...

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Dettagli Bibliografici
Autori principali: Duan, Jinghua, Vogt, Frederick G, Li, Xiaojian, Hayes, Don, Mansour, Heidi M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787929/
https://ncbi.nlm.nih.gov/pubmed/24092972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S48631
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