Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery

The aim of this study was to design and develop respirable antibiotics moxifloxacin (MOXI) hydrochloride and ofloxacin (OFLX) microparticles and nanoparticles, and multifunctional antibiotics particles with or without lung surfactant 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) for targeted dr...

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Detalles Bibliográficos
Main Authors: Duan, Jinghua, Vogt, Frederick G, Li, Xiaojian, Hayes, Don, Mansour, Heidi M
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787929/
https://ncbi.nlm.nih.gov/pubmed/24092972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S48631
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