Design and development of innovative microparticulate/nanoparticulate inhalable dry powders of a novel synthetic trifluorinated chalcone derivative and Nrf2 agonist

Chalcone derivatives are shown to possess excellent anti-inflammatory and anti-oxidant properties which are of great interest in treating respiratory diseases such as acute lung injury (ALI), acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and pulmonary fibr...

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Udgivet i:Sci Rep
Main Authors: Muralidharan, Priya, Jones, Brielle, Allaway, Graham, Biswal, Shyam S., Mansour, Heidi M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666129/
https://ncbi.nlm.nih.gov/pubmed/33188247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76585-2
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