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Design, Characterization, and Aerosol Dispersion Performance Modeling of Advanced Spray-Dried Microparticulate/Nanoparticulate Mannitol Powders for Targeted Pulmonary Delivery as Dry Powder Inhalers

Background: The purpose was to design and characterize inhalable microparticulate/nanoparticulate dry powders of mannitol with essential particle properties for targeted dry powder delivery for cystic fibrosis mucolytic treatment by dilute organic solution spray drying, and, in addition, to tailor a...

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Autors principals: Li, Xiaojian, Vogt, Frederick G., Hayes, Don, Mansour, Heidi M.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967386/
https://ncbi.nlm.nih.gov/pubmed/24502451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2013.1078
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