Physicochemical characterization and aerosol dispersion performance of organic solution advanced spray-dried cyclosporine A multifunctional particles for dry powder inhalation aerosol delivery

In this systematic and comprehensive study, inhalation powders of the polypeptide immunosuppressant drug – cyclosporine A – for lung delivery as dry powder inhalers (DPIs) were successfully designed, developed, and optimized. Several spray drying pump rates were rationally chosen. Comprehensive phys...

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Bibliographic Details
Main Authors: Wu, Xiao, Zhang, Weifen, Hayes, Don, Mansour, Heidi M
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2013
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615928/
https://ncbi.nlm.nih.gov/pubmed/23569375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S40904
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