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Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation

The aim of this study was to design, develop, and optimize respirable tacrolimus microparticles and nanoparticles and multifunctional tacrolimus lung surfactant mimic particles for targeted dry powder inhalation delivery as a pulmonary nanomedicine. Particles were rationally designed and produced at...

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Detalhes bibliográficos
Main Authors: Wu, Xiao, Hayes, Don, Zwischenberger, Joseph B, Kuhn, Robert J, Mansour, Heidi M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569053/
https://ncbi.nlm.nih.gov/pubmed/23403805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S40166
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