Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery

The aim of this study was to design and develop respirable antibiotics moxifloxacin (MOXI) hydrochloride and ofloxacin (OFLX) microparticles and nanoparticles, and multifunctional antibiotics particles with or without lung surfactant 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) for targeted dr...

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Main Authors: Duan, Jinghua, Vogt, Frederick G, Li, Xiaojian, Hayes, Don, Mansour, Heidi M
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787929/
https://ncbi.nlm.nih.gov/pubmed/24092972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S48631
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