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Novel lipoidal amine-based nanocarrier formulations for siRNA delivery

BACKGROUND: Lack of safe and efficient delivery of siRNA remains the greatest hurdle for the therapeutic application of siRNA. This article reports synthesis and evaluation of novel lipoidal amine-based nanocarrier (LANC) formulations for siRNA delivery. METHOD: Physicochemical properties were analy...

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Autores principales: Zhou, Chenguang, Zhang, Yue, Lee, L James, Lee, Robert J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568956/
https://ncbi.nlm.nih.gov/pubmed/22838067
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