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Poly(amidoamine) Dendrimer Nanocarriers and Their Aerosol Formulations for siRNA Delivery to the Lung Epithelium

[Image: see text] Small interfering RNA (siRNA)-based therapies have great promise in the treatment of a number of prevalent pulmonary disorders including lung cancer, asthma and cystic fibrosis. However, progress in this area has been hindered due to the lack of carriers that can efficiently delive...

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Detalhes bibliográficos
Main Authors: Conti, Denise S., Brewer, Daniel, Grashik, Jordan, Avasarala, Sumant, da Rocha, Sandro R. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051247/
https://ncbi.nlm.nih.gov/pubmed/24811243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4006358
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