Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma

Tumors are largely classified by histological appearance, yet morphological features do not necessarily predict cellular origin. To determine the origin of pancreatic ductal adenocarcinoma (PDA), we labeled and traced pancreatic cell populations after induction of a PDA-initiating Kras mutation. Our...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Kopp, Janel L., von Figura, Guido, Mayes, Erin, Liu, Fen-Fen, Dubois, Claire L., Morris, John P., Pan, Fong Cheng, Akiyama, Haruhiko, Wright, Christopher V. E., Jensen, Kristin, Hebrok, Matthias, Sander, Maike
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568632/
https://ncbi.nlm.nih.gov/pubmed/23201164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.10.025
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars