Asymmetric synthesis of host-directed inhibitors of myxoviruses

High-throughput screening (HTS) previously identified benzimidazole 1 (JMN3-003) as a compound with broad antiviral activity against different influenza viruses and paramyxovirus strains. In pursuit of a lead compound from this series for development, we sought to increase both the potency and the a...

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Detalles Bibliográficos
Autores principales: Moore, Terry W, Sana, Kasinath, Yan, Dan, Thepchatri, Pahk, Ndungu, John M, Saindane, Manohar T, Lockwood, Mark A, Natchus, Michael G, Liotta, Dennis C, Plemper, Richard K, Snyder, James P, Sun, Aiming
Formato: Artigo
Lenguaje:Inglês
Publicado: Beilstein-Institut 2013
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Full Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566758/
https://ncbi.nlm.nih.gov/pubmed/23400228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.23
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