Asymmetric synthesis of host-directed inhibitors of myxoviruses

High-throughput screening (HTS) previously identified benzimidazole 1 (JMN3-003) as a compound with broad antiviral activity against different influenza viruses and paramyxovirus strains. In pursuit of a lead compound from this series for development, we sought to increase both the potency and the a...

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Hlavní autoři: Moore, Terry W, Sana, Kasinath, Yan, Dan, Thepchatri, Pahk, Ndungu, John M, Saindane, Manohar T, Lockwood, Mark A, Natchus, Michael G, Liotta, Dennis C, Plemper, Richard K, Snyder, James P, Sun, Aiming
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566758/
https://ncbi.nlm.nih.gov/pubmed/23400228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.23
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