Potent Host-Directed Small-Molecule Inhibitors of Myxovirus RNA-Dependent RNA-Polymerases

Therapeutic targeting of host cell factors required for virus replication rather than of pathogen components opens new perspectives to counteract virus infections. Anticipated advantages of this approach include a heightened barrier against the development of viral resistance and a broadened pathoge...

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Detalhes bibliográficos
Main Authors: Krumm, Stefanie A., Ndungu, J. Maina, Yoon, Jeong-Joong, Dochow, Melanie, Sun, Aiming, Natchus, Michael, Snyder, James P., Plemper, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095640/
https://ncbi.nlm.nih.gov/pubmed/21603574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020069
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