Llwytho...

Spring-Loaded Mechanism of DNA Unwinding by Heptitis C Virus NS3 Helicase

NS3 is an essential helicase for replication of Hepatitis C virus, and is a model enzyme for investigating helicase function. Using single molecule fluorescence analysis, we show that NS3 unwinds DNA in discrete steps of approximately 3-bp. Dwell time analysis indicates that about three hidden steps...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Myong, Sua, Bruno, Michael M., Pyle, Anna M., Ha, Taekjip
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565428/
https://ncbi.nlm.nih.gov/pubmed/17656723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1144130
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