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Evolutionary conservation of codon optimality reveals hidden signatures of co-translational folding
The choice of codons can influence local translation kinetics during protein synthesis. Whether codon preference is linked to co-translational regulation of polypeptide folding remains unclear. Here, we derive a revised translational efficiency scale that incorporates the competition between tRNA su...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565066/ https://ncbi.nlm.nih.gov/pubmed/23262490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2466 |
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