Glutaminyl Cyclases as Novel Targets for the Treatment of Septic Arthritis

Background. Septic arthritis is a severe and rapidly debilitating disease mainly caused by Staphylococcus aureus. Here, we assess the antiarthritic efficiency of glutaminyl cyclase (QC) inhibitors. Methods. Mice were inoculated with an arthritogenic amount of S. aureus intravenously or by local admi...

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Autores principales: Hellvard, Annelie, Maresz, Katarzyna, Schilling, Stephan, Graubner, Sigrid, Heiser, Ulrich, Jonsson, Roland, Cynis, Holger, Demuth, Hans-Ulrich, Potempa, Jan, Mydel, Piotr
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563304/
https://ncbi.nlm.nih.gov/pubmed/23204180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis729
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