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Glutaminyl Cyclases as Novel Targets for the Treatment of Septic Arthritis

Background. Septic arthritis is a severe and rapidly debilitating disease mainly caused by Staphylococcus aureus. Here, we assess the antiarthritic efficiency of glutaminyl cyclase (QC) inhibitors. Methods. Mice were inoculated with an arthritogenic amount of S. aureus intravenously or by local admi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hellvard, Annelie, Maresz, Katarzyna, Schilling, Stephan, Graubner, Sigrid, Heiser, Ulrich, Jonsson, Roland, Cynis, Holger, Demuth, Hans-Ulrich, Potempa, Jan, Mydel, Piotr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563304/
https://ncbi.nlm.nih.gov/pubmed/23204180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis729
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