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Glutaminyl Cyclases as Novel Targets for the Treatment of Septic Arthritis

Background. Septic arthritis is a severe and rapidly debilitating disease mainly caused by Staphylococcus aureus. Here, we assess the antiarthritic efficiency of glutaminyl cyclase (QC) inhibitors. Methods. Mice were inoculated with an arthritogenic amount of S. aureus intravenously or by local admi...

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Hlavní autoři: Hellvard, Annelie, Maresz, Katarzyna, Schilling, Stephan, Graubner, Sigrid, Heiser, Ulrich, Jonsson, Roland, Cynis, Holger, Demuth, Hans-Ulrich, Potempa, Jan, Mydel, Piotr
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563304/
https://ncbi.nlm.nih.gov/pubmed/23204180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis729
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