Glutaminyl Cyclase Knock-out Mice Exhibit Slight Hypothyroidism but No Hypogonadism: IMPLICATIONS FOR ENZYME FUNCTION AND DRUG DEVELOPMENT

Glutaminyl cyclases (QCs) catalyze the formation of pyroglutamate (pGlu) residues at the N terminus of peptides and proteins. Hypothalamic pGlu hormones, such as thyrotropin-releasing hormone and gonadotropin-releasing hormone are essential for regulation of metabolism and fertility in the hypothala...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schilling, Stephan, Kohlmann, Stephanie, Bäuscher, Christoph, Sedlmeier, Reinhard, Koch, Birgit, Eichentopf, Rico, Becker, Andreas, Cynis, Holger, Hoffmann, Torsten, Berg, Sabine, Freyse, Ernst-Joachim, von Hörsten, Stephan, Rossner, Steffen, Graubner, Sigrid, Demuth, Hans-Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077621/
https://ncbi.nlm.nih.gov/pubmed/21330373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.229385
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados