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H1 linker histone promotes epigenetic silencing by regulating both DNA methylation and histone H3 methylation

Epigenetic silencing in mammals involves DNA methylation and posttranslational modifications of core histones. Here we show that the H1 linker histone plays a key role in regulating both DNA methylation and histone H3 methylation at the H19 and Gtl2 loci in mouse ES cells. Some, but not all, murine...

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書目詳細資料
Main Authors: Yang, Seung-Min, Kim, Byung Ju, Norwood Toro, Laura, Skoultchi, Arthur I.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562819/
https://ncbi.nlm.nih.gov/pubmed/23302691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213266110
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