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DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation

Epigenetic inheritance mechanisms play fundamental roles in maintaining cellular memory of gene expression states. In fission yeast, histone H3 lysine 9 (H3K9) is methylated (H3K9me) at heterochromatic domains. These domains can be epigenetically inherited when epe1(+), encoding an enzyme that promo...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Wang, Xiaoyi, Moazed, Danesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718040/
https://ncbi.nlm.nih.gov/pubmed/28302794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaj2114
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