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The Methyltransferase Activity of Clr4(Suv39h) triggers RNAi Independently of Histone H3K9 Methylation
In fission yeast, pericentromeric dg and dh repeats are transcribed and give rise to small interfering RNAs (siRNAs) by a mechanism that depends on the Clr4(suv39h) histone H3 lysine 9 (H3K9) methyltransferase. Here we show that Clr4 activity promotes the assembly of a tripartite complex composed of...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941148/ https://ncbi.nlm.nih.gov/pubmed/20705239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.07.017 |
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