Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development

Here we examined the involvement of Notch signaling in the endochondral ossification process, which is crucial for osteoarthritis (OA) development. Intracellular domains of Notch1 and -2 were translocated into the nucleus of chondrocytes with their differentiation in mouse limb cartilage and in mous...

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Detalhes bibliográficos
Main Authors: Hosaka, Yoko, Saito, Taku, Sugita, Shurei, Hikata, Tomohiro, Kobayashi, Hiroshi, Fukai, Atsushi, Taniguchi, Yuki, Hirata, Makoto, Akiyama, Haruhiko, Chung, Ung-il, Kawaguchi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562777/
https://ncbi.nlm.nih.gov/pubmed/23319657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207458110
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