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Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development

Here we examined the involvement of Notch signaling in the endochondral ossification process, which is crucial for osteoarthritis (OA) development. Intracellular domains of Notch1 and -2 were translocated into the nucleus of chondrocytes with their differentiation in mouse limb cartilage and in mous...

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Hlavní autoři: Hosaka, Yoko, Saito, Taku, Sugita, Shurei, Hikata, Tomohiro, Kobayashi, Hiroshi, Fukai, Atsushi, Taniguchi, Yuki, Hirata, Makoto, Akiyama, Haruhiko, Chung, Ung-il, Kawaguchi, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562777/
https://ncbi.nlm.nih.gov/pubmed/23319657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207458110
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