Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development

Here we examined the involvement of Notch signaling in the endochondral ossification process, which is crucial for osteoarthritis (OA) development. Intracellular domains of Notch1 and -2 were translocated into the nucleus of chondrocytes with their differentiation in mouse limb cartilage and in mous...

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Bibliografske podrobnosti
Main Authors: Hosaka, Yoko, Saito, Taku, Sugita, Shurei, Hikata, Tomohiro, Kobayashi, Hiroshi, Fukai, Atsushi, Taniguchi, Yuki, Hirata, Makoto, Akiyama, Haruhiko, Chung, Ung-il, Kawaguchi, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562777/
https://ncbi.nlm.nih.gov/pubmed/23319657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207458110
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